ea0029p1789 | Thyroid cancer | ICEECE2012
Kowalska A.
, Gasior-Perczak D.
, Palyga I.
, Siolek M.
, Kozak-Klonowska B.
, Kowalik A.
, Lubinski J.
, Cybulski C.
, Mezyk R.
, Gozdz S.
Introduction: CHEK2 is a gene encoding a protein involved in the mechanism of repairing damaged DNA. Mutations in the CHEK2 gene are associated with an increased risk of various neoplasms. The most common mutations in the Polish population are: I157T, less frequently IVS2+1G> A and 1100delC.Materials: The study consisted of 277 patients with papillary thyroid carcinoma: 252 female, 25 male, aged 15 to 76 years.Method: Patients ...